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Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical

Bacillus anthracis, the causative agent of anthrax, is a worldwide problem because of the need for effective treatment of respiratory infections shortly after exposure. One potential key enzyme of B. anthracis to be targeted by antiproliferative drugs is ribonucleotide reductase. It provides deoxyri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Torrents, Eduard, Sahlin, Margareta, Biglino, Daniele, Gräslund, Astrid, Sjöberg, Britt-Marie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312384/
https://ncbi.nlm.nih.gov/pubmed/16322104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506410102
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