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Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical

Bacillus anthracis, the causative agent of anthrax, is a worldwide problem because of the need for effective treatment of respiratory infections shortly after exposure. One potential key enzyme of B. anthracis to be targeted by antiproliferative drugs is ribonucleotide reductase. It provides deoxyri...

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Bibliografske podrobnosti
Main Authors: Torrents, Eduard, Sahlin, Margareta, Biglino, Daniele, Gräslund, Astrid, Sjöberg, Britt-Marie
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312384/
https://ncbi.nlm.nih.gov/pubmed/16322104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506410102
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