A unique cysteine-rich zinc finger domain present in a majority of class II ribonucleotide reductases mediates catalytic turnover

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to the corresponding deoxyribonucleotides, used in DNA synthesis and repair. Two different mechanisms help deliver the required electrons to the RNR active site. Formate can be used as reductant directly in the active site, o...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Loderer, Christoph, Jonna, Venkateswara Rao, Crona, Mikael, Rozman Grinberg, Inna, Sahlin, Margareta, Hofer, Anders, Lundin, Daniel, Sjöberg, Britt-Marie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2017
Onderwerpen:
Enzymology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704485/
https://ncbi.nlm.nih.gov/pubmed/28972190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806331
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