A unique cysteine-rich zinc finger domain present in a majority of class II ribonucleotide reductases mediates catalytic turnover

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to the corresponding deoxyribonucleotides, used in DNA synthesis and repair. Two different mechanisms help deliver the required electrons to the RNR active site. Formate can be used as reductant directly in the active site, o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Loderer, Christoph, Jonna, Venkateswara Rao, Crona, Mikael, Rozman Grinberg, Inna, Sahlin, Margareta, Hofer, Anders, Lundin, Daniel, Sjöberg, Britt-Marie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704485/
https://ncbi.nlm.nih.gov/pubmed/28972190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806331
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