A unique cysteine-rich zinc finger domain present in a majority of class II ribonucleotide reductases mediates catalytic turnover

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to the corresponding deoxyribonucleotides, used in DNA synthesis and repair. Two different mechanisms help deliver the required electrons to the RNR active site. Formate can be used as reductant directly in the active site, o...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Loderer, Christoph, Jonna, Venkateswara Rao, Crona, Mikael, Rozman Grinberg, Inna, Sahlin, Margareta, Hofer, Anders, Lundin, Daniel, Sjöberg, Britt-Marie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704485/
https://ncbi.nlm.nih.gov/pubmed/28972190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806331
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