טוען...
Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format
Ribonucleotide reductase (RNR) catalyzes reduction of the four different ribonucleotides to their corresponding deoxyribonucleotides and is the rate-limiting enzyme in DNA synthesis. RNR is a well-established target for the antiproliferative drugs Gemzar and Hydrea, for antisense therapy, and in com...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382500/ https://ncbi.nlm.nih.gov/pubmed/22665797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113051109 |
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