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The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

The spatial organization of chromosomes influences many nuclear processes including gene expression. The cohesin complex shapes the 3D genome by looping together CTCF sites along chromosomes. We show here that chromatin loop size can be increased and that the duration with which cohesin embraces DNA...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Haarhuis, Judith H.I., van der Weide, Robin H., Blomen, Vincent A., Yáñez-Cuna, J. Omar, Amendola, Mario, van Ruiten, Marjon S., Krijger, Peter H.L., Teunissen, Hans, Medema, René H., van Steensel, Bas, Brummelkamp, Thijn R., de Wit, Elzo, Rowland, Benjamin D.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422210/
https://ncbi.nlm.nih.gov/pubmed/28475897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.013
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