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The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension
The spatial organization of chromosomes influences many nuclear processes including gene expression. The cohesin complex shapes the 3D genome by looping together CTCF sites along chromosomes. We show here that chromatin loop size can be increased and that the duration with which cohesin embraces DNA...
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| Veröffentlicht in: | Cell |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422210/ https://ncbi.nlm.nih.gov/pubmed/28475897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.013 |
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