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The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension
The spatial organization of chromosomes influences many nuclear processes including gene expression. The cohesin complex shapes the 3D genome by looping together CTCF sites along chromosomes. We show here that chromatin loop size can be increased and that the duration with which cohesin embraces DNA...
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Publié dans: | Cell |
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Auteurs principaux: | , , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Cell Press
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422210/ https://ncbi.nlm.nih.gov/pubmed/28475897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.013 |
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