Tumor-infiltrating Merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival

Tumor-infiltrating CD8(+) T cells are associated with improved survival of patients with Merkel cell carcinoma (MCC), an aggressive skin cancer causally linked to Merkel cell polyomavirus (MCPyV). However, CD8(+) T-cell infiltration is robust in only 4%–18% of MCC tumors. We characterized the T-cell...

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發表在:Cancer Immunol Res
Main Authors: Miller, Natalie J., Church, Candice D., Dong, Lichun, Crispin, David, Fitzgibbon, Matthew P., Lachance, Kristina, Jing, Lichen, Shinohara, Michi, Gavvovidis, Ioannis, Willimsky, Gerald, McIntosh, Martin, Blankenstein, Thomas, Koelle, David M., Nghiem, Paul
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421625/
https://ncbi.nlm.nih.gov/pubmed/28093446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0210
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