Merkel cell polyomavirus-specific CD8+ and CD4+ T-cell responses identified in Merkel cell carcinomas and blood

PURPOSE: Merkel cell polyomavirus (MCPyV) is prevalent in the general population, integrates into most Merkel cell carcinomas (MCCs) and encodes oncoproteins required for MCC tumor growth. We sought to characterize T-cell responses directed against viral proteins that drive this cancer as a step tow...

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Detalhes bibliográficos
Main Authors: Iyer, Jayasri G., Afanasiev, Olga K., McClurkan, Christopher, Paulson, Kelly, Nagase, Kotaro, Jing, Lichen, Marshak, Joshua O., Dong, Lichun, Carter, Joseph, Lai, Ivy, Farrar, Erik, Byrd, David, Galloway, Denise, Yee, Cassian, Koelle, David M., Nghiem, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207011/
https://ncbi.nlm.nih.gov/pubmed/21908576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1513
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