Diagnostic Biopsy Does Not Commonly Induce Intratumoral CD8 T Cell Infiltration in Merkel Cell Carcinoma

BACKGROUND: Merkel cell carcinoma is a polyomavirus-associated cancer that is strongly linked with T lymphocyte immune suppression in epidemiologic studies. CD8+ T cell infiltration into MCC tumors (intratumoral) has recently been shown to be strongly predictive of improved survival. In contrast, th...

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Autors principals: Koba, Shinichi, Paulson, Kelly G., Nagase, Kotaro, Tegeder, Andrew, Thibodeau, Renee, Iyer, Jayasri G., Narisawa, Yutaka, Nghiem, Paul
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409202/
https://ncbi.nlm.nih.gov/pubmed/22859987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041465
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