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Polyomavirus-driven Merkel cell carcinoma: prospects for therapeutic vaccine development

Great strides have been made in cancer immunotherapy including the breakthrough successes of anti-PD-(L)1 checkpoint inhibitors. In Merkel cell carcinoma (MCC), a rare and aggressive skin cancer, PD-(L)1 blockade is highly effective. Yet, ~50% of patients either do not respond to therapy or develop...

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Publicat a:Mol Carcinog
Autors principals: Tabachnick-Cherny, Shira, Pulliam, Thomas, Church, Candice, Koelle, David M., Nghiem, Paul
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238237/
https://ncbi.nlm.nih.gov/pubmed/32219902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23190
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