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Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas
Merkel cell carcinoma (MCC) is a rare but often deadly skin cancer that is typically caused by the Merkel cell polyomavirus (MCPyV). Polyomavirus T-antigen oncoproteins are persistently expressed in virus-positive MCCs (˜80% of cases), while remarkably high numbers of tumor-associated neoantigens ar...
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| Publicado no: | Immunotherapy |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827814/ https://ncbi.nlm.nih.gov/pubmed/27381685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2016-0009 |
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