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Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas

Merkel cell carcinoma (MCC) is a rare but often deadly skin cancer that is typically caused by the Merkel cell polyomavirus (MCPyV). Polyomavirus T-antigen oncoproteins are persistently expressed in virus-positive MCCs (˜80% of cases), while remarkably high numbers of tumor-associated neoantigens ar...

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Detaylı Bibliyografya
Yayımlandı:Immunotherapy
Asıl Yazarlar: Vandeven, Natalie, Nghiem, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Future Medicine Ltd 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827814/
https://ncbi.nlm.nih.gov/pubmed/27381685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2016-0009
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