Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Miller, Natalie J., Church, Candice D., Fling, Steven P., Kulikauskas, Rima, Ramchurren, Nirasha, Shinohara, Michi M., Kluger, Harriet M., Bhatia, Shailender, Lundgren, Lisa, Cheever, Martin A., Topalian, Suzanne L., Nghiem, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258401/
https://ncbi.nlm.nih.gov/pubmed/30482247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0450-7
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