Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Miller, Natalie J., Church, Candice D., Fling, Steven P., Kulikauskas, Rima, Ramchurren, Nirasha, Shinohara, Michi M., Kluger, Harriet M., Bhatia, Shailender, Lundgren, Lisa, Cheever, Martin A., Topalian, Suzanne L., Nghiem, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258401/
https://ncbi.nlm.nih.gov/pubmed/30482247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0450-7
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