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Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific...

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Podrobná bibliografie
Vydáno v:J Immunother Cancer
Hlavní autoři: Miller, Natalie J., Church, Candice D., Fling, Steven P., Kulikauskas, Rima, Ramchurren, Nirasha, Shinohara, Michi M., Kluger, Harriet M., Bhatia, Shailender, Lundgren, Lisa, Cheever, Martin A., Topalian, Suzanne L., Nghiem, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258401/
https://ncbi.nlm.nih.gov/pubmed/30482247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0450-7
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