Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific...

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Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Miller, Natalie J., Church, Candice D., Fling, Steven P., Kulikauskas, Rima, Ramchurren, Nirasha, Shinohara, Michi M., Kluger, Harriet M., Bhatia, Shailender, Lundgren, Lisa, Cheever, Martin A., Topalian, Suzanne L., Nghiem, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258401/
https://ncbi.nlm.nih.gov/pubmed/30482247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0450-7
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