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PIN1 Modulates Huntingtin Levels and Aggregate Accumulation: An In vitro Model
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder characterized by a polyglutamine expansion within the N-terminal region of huntingtin protein (HTT). Cellular mechanisms promoting mutant huntingtin (mHTT) clearance are of great interest in HD pathology as they can...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5420564/ https://ncbi.nlm.nih.gov/pubmed/28533744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00121 |
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