Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models

Huntington's disease (HD) is a devastating neurodegenerative disorder with no disease-modifying treatments available. The disease is caused by expansion of a CAG trinucleotide repeat and manifests with progressive motor abnormalities, psychiatric symptoms, and cognitive decline. Expression of a...

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Bibliografski detalji
Glavni autori: Sontag, Emily Mitchell, Lotz, Gregor P., Agrawal, Namita, Tran, Andrew, Aron, Rebecca, Yang, Guocheng, Necula, Mihaela, Lau, Alice, Finkbeiner, Steven, Glabe, Charles, Marsh, J. Lawrence, Muchowski, Paul J., Thompson, Leslie M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546821/
https://ncbi.nlm.nih.gov/pubmed/22875942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0895-12.2012
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