Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models

Huntington's disease (HD) is a devastating neurodegenerative disorder with no disease-modifying treatments available. The disease is caused by expansion of a CAG trinucleotide repeat and manifests with progressive motor abnormalities, psychiatric symptoms, and cognitive decline. Expression of a...

Full description

Saved in:
Bibliographic Details
Main Authors: Sontag, Emily Mitchell, Lotz, Gregor P., Agrawal, Namita, Tran, Andrew, Aron, Rebecca, Yang, Guocheng, Necula, Mihaela, Lau, Alice, Finkbeiner, Steven, Glabe, Charles, Marsh, J. Lawrence, Muchowski, Paul J., Thompson, Leslie M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546821/
https://ncbi.nlm.nih.gov/pubmed/22875942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0895-12.2012
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items