Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models

Huntington's disease (HD) is a devastating neurodegenerative disorder with no disease-modifying treatments available. The disease is caused by expansion of a CAG trinucleotide repeat and manifests with progressive motor abnormalities, psychiatric symptoms, and cognitive decline. Expression of a...

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Detaylı Bibliyografya
Asıl Yazarlar: Sontag, Emily Mitchell, Lotz, Gregor P., Agrawal, Namita, Tran, Andrew, Aron, Rebecca, Yang, Guocheng, Necula, Mihaela, Lau, Alice, Finkbeiner, Steven, Glabe, Charles, Marsh, J. Lawrence, Muchowski, Paul J., Thompson, Leslie M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546821/
https://ncbi.nlm.nih.gov/pubmed/22875942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0895-12.2012
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