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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling
Classically, G protein-coupled receptor (GPCR) stimulation promotes G protein signaling at the plasma membrane, followed by rapid β-arrestin-mediated desensitization and receptor internalization into endosomes. However, it has been demonstrated that some GPCRs activate G proteins from within interna...
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| Izdano u: | Cell |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418658/ https://ncbi.nlm.nih.gov/pubmed/27499021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.004 |
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