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Effects of macromolecular crowding agents on protein folding in vitro and in silico

Proteins fold and function inside cells which are environments very different from that of dilute buffer solutions most often used in traditional experiments. The crowded milieu results in excluded-volume effects, increased bulk viscosity and amplified chances for inter-molecular interactions. These...

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Vydáno v:Biophys Rev
Hlavní autoři: Christiansen, Alexander, Wang, Qian, Cheung, Margaret S., Wittung-Stafshede, Pernilla
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418436/
https://ncbi.nlm.nih.gov/pubmed/28510156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0108-0
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