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Effects of macromolecular crowding agents on protein folding in vitro and in silico

Proteins fold and function inside cells which are environments very different from that of dilute buffer solutions most often used in traditional experiments. The crowded milieu results in excluded-volume effects, increased bulk viscosity and amplified chances for inter-molecular interactions. These...

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Bibliografiske detaljer
Udgivet i:Biophys Rev
Main Authors: Christiansen, Alexander, Wang, Qian, Cheung, Margaret S., Wittung-Stafshede, Pernilla
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418436/
https://ncbi.nlm.nih.gov/pubmed/28510156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0108-0
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