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Effects of macromolecular crowding agents on protein folding in vitro and in silico

Proteins fold and function inside cells which are environments very different from that of dilute buffer solutions most often used in traditional experiments. The crowded milieu results in excluded-volume effects, increased bulk viscosity and amplified chances for inter-molecular interactions. These...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Main Authors: Christiansen, Alexander, Wang, Qian, Cheung, Margaret S., Wittung-Stafshede, Pernilla
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418436/
https://ncbi.nlm.nih.gov/pubmed/28510156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0108-0
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