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Effects of macromolecular crowding agents on protein folding in vitro and in silico

Proteins fold and function inside cells which are environments very different from that of dilute buffer solutions most often used in traditional experiments. The crowded milieu results in excluded-volume effects, increased bulk viscosity and amplified chances for inter-molecular interactions. These...

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Dades bibliogràfiques
Publicat a:Biophys Rev
Autors principals: Christiansen, Alexander, Wang, Qian, Cheung, Margaret S., Wittung-Stafshede, Pernilla
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418436/
https://ncbi.nlm.nih.gov/pubmed/28510156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-013-0108-0
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