Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer

The Rho GTPases Rac (Ras-related C3 botulinum toxin substrate) and Cdc42 (cell division control protein 42 homolog) regulate cell functions governing cancer malignancy, including cell polarity, migration, and cell cycle progression. Accordingly, our recently developed Rac inhibitor EHop-016 (IC(50),...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cancer Ther
मुख्य लेखकों: Humphries-Bickley, Tessa, Castillo-Pichardo, Linette, Hernandez-O’Farrill, Eliud, Borrero-Garcia, Luis D., Forestier-Roman, Ingrid, Gerena, Yamil, Blanco, Manuel, Rivera-Robles, Michael J, Rodriguez-Medina, José R, Cubano, Luis A, Vlaar, Cornelis P, Dharmawardhane, Suranganie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418092/
https://ncbi.nlm.nih.gov/pubmed/28450422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0442
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