Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

The 26S proteasome is the macromolecular machine responsible for ATP/ubiquitin dependent degradation. As aberration in proteasomal degradation has been implicated in many human diseases, structural analysis of the human 26S proteasome complex is essential to advance our understanding of its action a...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Wang, Xiaorong, Cimermancic, Peter, Yu, Clinton, Schweitzer, Andreas, Chopra, Nikita, Engel, James L., Greenberg, Charles, Huszagh, Alexander S., Beck, Florian, Sakata, Eri, Yang, Yingying, Novitsky, Eric J., Leitner, Alexander, Nanni, Paolo, Kahraman, Abdullah, Guo, Xing, Dixon, Jack E., Rychnovsky, Scott D., Aebersold, Ruedi, Baumeister, Wolfgang, Sali, Andrej, Huang, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417825/
https://ncbi.nlm.nih.gov/pubmed/28292943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.065326
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