Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

The 26S proteasome is the macromolecular machine responsible for ATP/ubiquitin dependent degradation. As aberration in proteasomal degradation has been implicated in many human diseases, structural analysis of the human 26S proteasome complex is essential to advance our understanding of its action a...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Wang, Xiaorong, Cimermancic, Peter, Yu, Clinton, Schweitzer, Andreas, Chopra, Nikita, Engel, James L., Greenberg, Charles, Huszagh, Alexander S., Beck, Florian, Sakata, Eri, Yang, Yingying, Novitsky, Eric J., Leitner, Alexander, Nanni, Paolo, Kahraman, Abdullah, Guo, Xing, Dixon, Jack E., Rychnovsky, Scott D., Aebersold, Ruedi, Baumeister, Wolfgang, Sali, Andrej, Huang, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417825/
https://ncbi.nlm.nih.gov/pubmed/28292943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.065326
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