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Toward an Integrated Structural Model of the 26S Proteasome

The 26S proteasome is the end point of the ubiquitin-proteasome pathway and degrades ubiquitylated substrates. It is composed of the 20S core particle (CP), where degradation occurs, and the 19S regulatory particle (RP), which ensures substrate specificity of degradation. Whereas the CP is resolved...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Förster, Friedrich, Lasker, Keren, Nickell, Stephan, Sali, Andrej, Baumeister, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938054/
https://ncbi.nlm.nih.gov/pubmed/20467039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R000002-MCP201
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