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An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome

The 26S proteasome is the most downstream element of the ubiquitin-proteasome pathway of protein degradation. It is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP consists of 6 AAA-ATPases and at least 13 non-ATPase subunits. Based on a cryo-EM map of the 26S pro...

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Détails bibliographiques
Auteurs principaux: Förster, Friedrich, Lasker, Keren, Beck, Florian, Nickell, Stephan, Sali, Andrej, Baumeister, Wolfgang
Format: Artigo
Langue:Inglês
Publié: 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771176/
https://ncbi.nlm.nih.gov/pubmed/19653995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.145
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