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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

The 26S proteasome is at the executive end of the ubiquitin-proteasome pathway for the controlled degradation of intracellular proteins. While the structure of its 20S core particle (CP) has been determined by X-ray crystallography, the structure of the 19S regulatory particle (RP), which recruits s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lasker, Keren, Förster, Friedrich, Bohn, Stefan, Walzthoeni, Thomas, Villa, Elizabeth, Unverdorben, Pia, Beck, Florian, Aebersold, Ruedi, Sali, Andrej, Baumeister, Wolfgang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277140/
https://ncbi.nlm.nih.gov/pubmed/22307589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120559109
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