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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
The 26S proteasome is at the executive end of the ubiquitin-proteasome pathway for the controlled degradation of intracellular proteins. While the structure of its 20S core particle (CP) has been determined by X-ray crystallography, the structure of the 19S regulatory particle (RP), which recruits s...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277140/ https://ncbi.nlm.nih.gov/pubmed/22307589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120559109 |
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