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Research Resource: Transcriptional Response to Glucocorticoids in Childhood Acute Lymphoblastic Leukemia

Glucocorticoids (GC) induce apoptosis in lymphoblasts and are thus essential in the treatment of acute lymphoblastic leukemia (ALL). Their effects result from gene regulations via the GC receptor (NR3C1/GR), but it is unknown how these changes evolve, what the primary GR targets are, and to what ext...

詳細記述

保存先:
書誌詳細
出版年:Mol Endocrinol
主要な著者: Rainer, Johannes, Lelong, Julien, Bindreither, Daniel, Mantinger, Christine, Ploner, Christian, Geley, Stephan, Kofler, Reinhard
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417158/
https://ncbi.nlm.nih.gov/pubmed/22074950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1213
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