Research Resource: Transcriptional Response to Glucocorticoids in Childhood Acute Lymphoblastic Leukemia

Glucocorticoids (GC) induce apoptosis in lymphoblasts and are thus essential in the treatment of acute lymphoblastic leukemia (ALL). Their effects result from gene regulations via the GC receptor (NR3C1/GR), but it is unknown how these changes evolve, what the primary GR targets are, and to what ext...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Rainer, Johannes, Lelong, Julien, Bindreither, Daniel, Mantinger, Christine, Ploner, Christian, Geley, Stephan, Kofler, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Research Resource
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417158/
https://ncbi.nlm.nih.gov/pubmed/22074950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1213
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