Research Resource: Transcriptional Response to Glucocorticoids in Childhood Acute Lymphoblastic Leukemia

Glucocorticoids (GC) induce apoptosis in lymphoblasts and are thus essential in the treatment of acute lymphoblastic leukemia (ALL). Their effects result from gene regulations via the GC receptor (NR3C1/GR), but it is unknown how these changes evolve, what the primary GR targets are, and to what ext...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Rainer, Johannes, Lelong, Julien, Bindreither, Daniel, Mantinger, Christine, Ploner, Christian, Geley, Stephan, Kofler, Reinhard
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Research Resource
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417158/
https://ncbi.nlm.nih.gov/pubmed/22074950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1213
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