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Research Resource: Transcriptional Response to Glucocorticoids in Childhood Acute Lymphoblastic Leukemia
Glucocorticoids (GC) induce apoptosis in lymphoblasts and are thus essential in the treatment of acute lymphoblastic leukemia (ALL). Their effects result from gene regulations via the GC receptor (NR3C1/GR), but it is unknown how these changes evolve, what the primary GR targets are, and to what ext...
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| 發表在: | Mol Endocrinol |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Endocrine Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417158/ https://ncbi.nlm.nih.gov/pubmed/22074950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1213 |
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