PLZF/ZBTB16, a glucocorticoid response gene in acute lymphoblastic leukemia, interferes with glucocorticoid-induced apoptosis

Glucocorticoids (GCs) cause cell cycle arrest and apoptosis in lymphoid cells which is exploited to treat lymphoid malignancies. The mechanisms of these anti-leukemic GC effects are, however, poorly understood. We previously defined a list of GC-regulated genes by expression profiling in children wi...

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Библиографические подробности
Главные авторы: Wasim, Muhammad, Carlet, Michela, Mansha, Muhammad, Greil, Richard, Ploner, Christian, Trockenbacher, Alexander, Rainer, Johannes, Kofler, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: Pergamon 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892747/
https://ncbi.nlm.nih.gov/pubmed/20435142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.04.019
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