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The spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer

Prokaryotes memorize invader information by incorporating alien DNA as spacers into CRISPR arrays. Although the spacer size has been suggested to be predefined by the architecture of the acquisition complex, there is usually an unexpected heterogeneity. Here, we explored the causes of this heterogen...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Ming, Gong, Luyao, Zhao, Dahe, Zhou, Jian, Xiang, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416893/
https://ncbi.nlm.nih.gov/pubmed/28379481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx229
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