Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer

Clustered regularly interspaced short palindromic repeats (CRISPR), in combination with CRISPR associated (cas) genes, constitute CRISPR-Cas bacterial adaptive immune systems. To generate immunity, these systems acquire short sequences of nucleic acids from foreign invaders and incorporate these int...

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Bibliografiske detaljer
Main Authors: Richter, Corinna, Dy, Ron L., McKenzie, Rebecca E., Watson, Bridget N.J., Taylor, Corinda, Chang, James T., McNeil, Matthew B., Staals, Raymond H.J., Fineran, Peter C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117759/
https://ncbi.nlm.nih.gov/pubmed/24990370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku527
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