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Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system
CRISPR–Cas systems provide bacteria with adaptive immunity against foreign nucleic acids by acquiring short, invader-derived sequences called spacers. Here, we use high-throughput sequencing to analyse millions of spacer acquisition events in wild-type populations of Pectobacterium atrosepticum. Pla...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5059440/ https://ncbi.nlm.nih.gov/pubmed/27694798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12853 |
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