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CRISPR Interference Directs Strand Specific Spacer Acquisition

BACKGROUND: CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders. In Escherichia coli, transcripts of these loci are cl...

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Bibliografske podrobnosti
Main Authors: Swarts, Daan C., Mosterd, Cas, van Passel, Mark W. J., Brouns, Stan J. J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338789/
https://ncbi.nlm.nih.gov/pubmed/22558257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035888
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