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Molecular recordings by directed CRISPR spacer acquisition
The ability to write a stable record of identified molecular events into a specific genomic locus would enable the examination of long cellular histories and have many applications, ranging from developmental biology to synthetic devices. We show that the type I-E CRISPR-Cas system of E. coli can me...
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| Vydáno v: | Science |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994893/ https://ncbi.nlm.nih.gov/pubmed/27284167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf1175 |
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