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Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system
CRISPR–Cas systems provide bacteria with adaptive immunity against foreign nucleic acids by acquiring short, invader-derived sequences called spacers. Here, we use high-throughput sequencing to analyse millions of spacer acquisition events in wild-type populations of Pectobacterium atrosepticum. Pla...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5059440/ https://ncbi.nlm.nih.gov/pubmed/27694798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12853 |
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