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Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process
The clustered regularly interspaced short palindromic repeat (CRISPR)-Cas system mediates adaptive immunity against foreign nucleic acids in prokaryotes. However, efficient adaptation of a native CRISPR to purified viruses has only been observed for the type II-A system from a Streptococcus thermoph...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936756/ https://ncbi.nlm.nih.gov/pubmed/24265226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1154 |
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