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Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica
Recent studies on CRISPR adaptation revealed that priming is a major pathway of spacer acquisition, at least for the most prevalent type I systems. Priming is guided by a CRISPR RNA which fully/partially matches the invader DNA, but the plasticity of this RNA guide has not yet been characterized. In...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6582329/ https://ncbi.nlm.nih.gov/pubmed/30957847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz244 |
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