Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats

Trinucleotide repeats are a source of genome instability, causing replication fork stalling, chromosome fragility, and impaired repair. Specialized helicases play an important role in unwinding DNA structures to maintain genome stability. The Srs2 helicase unwinds DNA hairpins, facilitates replicati...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Nguyen, Jennifer H.G., Viterbo, David, Anand, Ranjith P., Verra, Lauren, Sloan, Laura, Richard, Guy-Franck, Freudenreich, Catherine H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416882/
https://ncbi.nlm.nih.gov/pubmed/28175398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx088
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki