Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation

Estrogen receptor (ER)α is a well-characterized ligand-dependent transcription factor. However, the global picture of its nongenomic functions remains to be illustrated. Here, we demonstrate a novel function of ERα during mitosis that facilitates estrogen-dependent cell proliferation. An E3 ubiquiti...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Okada, Maiko, Ohtake, Fumiaki, Nishikawa, Hiroyuki, Wu, Wenwen, Saeki, Yasushi, Takana, Keiji, Ohta, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414673/
https://ncbi.nlm.nih.gov/pubmed/26389696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1125
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