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The ubiquitin E3 ligase activity of BRCA1 and its biological functions

The basal-like breast cancer, a new category of breast cancer associated with poor prognosis and possibly unique chemosensitivity, is a current topic in the breast cancer field. Evidence from multiple sources strongly indicate that impairment of BRCA1 pathways is responsible for this phenotype, impl...

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Detalhes bibliográficos
Main Authors: Wu, Wenwen, Koike, Ayaka, Takeshita, Takashi, Ohta, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254412/
https://ncbi.nlm.nih.gov/pubmed/18179693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-3-1
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