The ubiquitin E3 ligase activity of BRCA1 and its biological functions

por Wu, Wenwen, Koike, Ayaka, Takeshita, Takashi, Ohta, Tomohiko
Publicado 2008

Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents

por Takeshita, Takashi, Wu, Wenwen, Koike, Ayaka, Fukuda, Mamoru, Ohta, Tomohiko
Publicado 2009

Late recurrence of breast cancer is associated with pro-cancerous immune microenvironment in the primary tumor

por Takeshita, Takashi, Yan, Li, Asaoka, Mariko, Rashid, Omar, Takabe, Kazuaki
Publicado en Sci Rep (2019)

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

por Sueta, Aiko, Yamamoto, Yutaka, Tomiguchi, Mai, Takeshita, Takashi, Yamamoto-Ibusuki, Mutsuko, Iwase, Hirotaka
Publicado en Oncotarget (2017)

A case of premenopausal breast cancer with symptomatic cerebellar metastasis successfully treated by systemic endocrine therapy alone: relationship to biological features

por Fujiki, Yoshitaka, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Goto, Lisa, Takeshita, Takashi, Iwase, Hirotaka
Publicado en Int Cancer Conf J (2016)

The Impact of Immunofunctional Phenotyping on the Malfunction of the Cancer Immunity Cycle in Breast Cancer

por Takeshita, Takashi, Torigoe, Toshihiko, Yan, Li, Huang, Jing Li, Yamashita, Hiroko, Takabe, Kazuaki
Publicado en Cancers (Basel) (2020)

An Integrative Analysis of PIK3CA Mutation, PTEN, and INPP4B Expression in Terms of Trastuzumab Efficacy in HER2-Positive Breast Cancer

por Sueta, Aiko, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Hayashi, Mitsuhiro, Takeshita, Takashi, Yamamoto, Satoko, Iwase, Hirotaka
Publicado en PLoS One (2014)

Clinical significance of plasma cell-free DNA mutations in PIK3CA, AKT1, and ESR1 gene according to treatment lines in ER-positive breast cancer

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Tomiguchi, Mai, Sueta, Aiko, Murakami, Keiichi, Iwase, Hirotaka
Publicado en Mol Cancer (2018)

High expression of polo-like kinase 1 is associated with TP53 inactivation, DNA repair deficiency, and worse prognosis in ER positive Her2 negative breast cancer

por Takeshita, Takashi, Asaoka, Mariko, Katsuta, Eriko, Photiadis, Sara J, Narayanan, Sumana, Yan, Li, Takabe, Kazuaki
Publicado en Am J Transl Res (2019)

High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer

por Katsuta, Eriko, Yan, Li, Takeshita, Takashi, McDonald, Kerry-Ann, Dasgupta, Subhamoy, Opyrchal, Mateusz, Takabe, Kazuaki
Publicado en Int J Mol Sci (2019)

Prognostic role of PIK3CA mutations of cell‐free DNA in early‐stage triple negative breast cancer

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto‐Ibusuki, Mutsuko, Inao, Toko, Sueta, Aiko, Fujiwara, Saori, Omoto, Yoko, Iwase, Hirotaka
Publicado en Cancer Sci (2015)

Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Inao, Toko, Sueta, Aiko, Fujiwara, Saori, Omoto, Yoko, Iwase, Hirotaka
Publicado en Oncotarget (2016)

Clinical features of lenvatinib treatment in elderly patients with advanced thyroid cancer

por Suyama, Koichi, Fujiwara, Saori, Takeshita, Takashi, Sueta, Aiko, Inao, Touko, Yamamoto-Ibusuki, Mutsuko, Yamamoto, Yutaka, Iwase, Hirotaka
Publicado en Mol Clin Oncol (2017)

Comparison of ESR1 Mutations in Tumor Tissue and Matched Plasma Samples from Metastatic Breast Cancer Patients

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Tomiguchi, Mai, Sueta, Aiko, Murakami, Keiichi, Omoto, Yoko, Iwase, Hirotaka
Publicado en Transl Oncol (2017)

Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Tomiguchi, Mai, Sueta, Aiko, Murakami, Keiichi, Omoto, Yoko, Iwase, Hirotaka
Publicado en Oncotarget (2017)

Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients

por Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Sueta, Aiko, Tomiguchi, Mai, Murakami, Keiichi, Omoto, Yoko, Iwase, Hirotaka
Publicado en BMC Cancer (2017)

PTIP Associated protein 1, PA1, Is an Independent Prognostic Factor for Lymphnode Negative Breast Cancer

por Takeshita, Takashi, Yamamoto-Ibusuki, Mutsuko, Yamamoto, Yutaka, Omoto, Yoko, Honda, Yumi, Iyama, Ken-ichi, Zhang, Zhenhuan, Iwase, Hirotaka
Publicado 2013

APOBEC3B gene expression as a novel predictive factor for pathological complete response to neoadjuvant chemotherapy in breast cancer

por Fujiki, Yoshitaka, Yamamoto, Yutaka, Sueta, Aiko, Yamamoto-Ibusuki, Mutsuko, Goto-Yamaguchi, Lisa, Tomiguchi, Mai, Takeshita, Takashi, Iwase, Hirotaka
Publicado en Oncotarget (2018)

Transcriptomic and functional pathway features were associated with survival after pathological complete response to neoadjuvant chemotherapy in breast cancer

por Takeshita, Takashi, Yan, Li, Peng, Xuan, Kimbung, Siker, Hatschek, Thomas, Hedenfalk, Ingrid A, Rashid, Omar M, Takabe, Kazuaki
Publicado en Am J Cancer Res (2020)

The localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer

por Fujiwara, Saori, Yamamoto-Ibusuk, Mutsuko, Yamamoto, Yutaka, Yamamoto, Satoko, Tomiguchi, Mai, Takeshita, Takashi, Hayashi, Mitsuhiro, Sueta, Aiko, Iwase, Hirotaka
Publicado 2014