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Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients
BACKGROUND: ESR1 mutations have attracted attention as a potentially important marker and treatment target in endocrine therapy-resistant breast cancer patients. The E380Q mutation, which is one of the ESR1 mutations, is associated with estradiol (E2) hypersensitivity, increased DNA binding to the e...
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| 出版年: | BMC Cancer |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5700624/ https://ncbi.nlm.nih.gov/pubmed/29166868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3779-2 |
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