Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients

BACKGROUND: ESR1 mutations have attracted attention as a potentially important marker and treatment target in endocrine therapy-resistant breast cancer patients. The E380Q mutation, which is one of the ESR1 mutations, is associated with estradiol (E2) hypersensitivity, increased DNA binding to the e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Takeshita, Takashi, Yamamoto, Yutaka, Yamamoto-Ibusuki, Mutsuko, Sueta, Aiko, Tomiguchi, Mai, Murakami, Keiichi, Omoto, Yoko, Iwase, Hirotaka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700624/
https://ncbi.nlm.nih.gov/pubmed/29166868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3779-2
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