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High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer

DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC). Its DNA amplification is often part of the targeted DNA-sequencing p...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Katsuta, Eriko, Yan, Li, Takeshita, Takashi, McDonald, Kerry-Ann, Dasgupta, Subhamoy, Opyrchal, Mateusz, Takabe, Kazuaki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981812/
https://ncbi.nlm.nih.gov/pubmed/31905596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010217
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