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High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer

DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC). Its DNA amplification is often part of the targeted DNA-sequencing p...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Katsuta, Eriko, Yan, Li, Takeshita, Takashi, McDonald, Kerry-Ann, Dasgupta, Subhamoy, Opyrchal, Mateusz, Takabe, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981812/
https://ncbi.nlm.nih.gov/pubmed/31905596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010217
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