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Assessment of disulfide and hinge modifications in monoclonal antibodies

During the last years there was a substantial increase in the use of antibodies and related proteins as therapeutics. The emphasis of the pharmaceutical industry is on IgG1, IgG2, and IgG4 antibodies, which are therefore in the focus of this article. In order to ensure appropriate quality control of...

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Detaylı Bibliyografya
Yayımlandı:Electrophoresis
Asıl Yazarlar: Moritz, Bernd, Stracke, Jan Olaf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413849/
https://ncbi.nlm.nih.gov/pubmed/27982442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201600425
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