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Taking the Hinge off: An Approach to Effector-Less Monoclonal Antibodies
A variety of Fc domain engineering approaches for abrogating the effector functions of mAbs exists. To address some of the limitations of the current Fc domain silencing approaches, we are exploring a less commonly considered option which relies on the deletion of the hinge. Removal of the hinge dom...
Gorde:
| Argitaratua izan da: | Antibodies (Basel) |
|---|---|
| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7709103/ https://ncbi.nlm.nih.gov/pubmed/32977708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9040050 |
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