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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies

Most therapeutic monoclonal antibodies (mAbs) licensed for human use or in clinical development are indicated for treatment of patients with cancer and inflammatory/autoimmune disease and as such, are designed to directly interact with the immune system. A major hurdle for the development and early...

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Detalhes bibliográficos
Main Authors: Brennan, Frank R, Morton, Laura Dill, Spindeldreher, Sebastian, Kiessling, Andrea, Allenspach, Roy, Hey, Adam, Muller, Patrick Y, Frings, Werner, Sims, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881251/
https://ncbi.nlm.nih.gov/pubmed/20421713
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