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Tregitopes and impaired antigen presentation: Drivers of the immunomodulatory effects of IVIg?

INTRODUCTION: Although intravenous immunoglobulin (IVIg) is commonly used in the clinic to treat various autoimmune and severe inflammatory diseases, the mode of action is not fully elucidated. This work investigates two proposed mechanisms: (1) the potential role of regulatory T‐cell epitopes (Treg...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Sordé, Laetitia, Spindeldreher, Sebastian, Palmer, Ed, Karle, Anette
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691310/
https://ncbi.nlm.nih.gov/pubmed/28560793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.167
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