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NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
Inflammation in the brain accompanies several high-impact neurological diseases including multiple sclerosis (MS), stroke, and Alzheimer’s disease. Neuroinflammation is sterile, as damage-associated molecular patterns rather than microbial pathogens elicit the response. The inflammasome, which leads...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413320/ https://ncbi.nlm.nih.gov/pubmed/28404595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150237 |
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