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NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

Neuroinflammation is the local reaction of the brain to infection, trauma, toxic molecules or protein aggregates. The brain resident macrophages, microglia, are able to trigger an appropriate response involving secretion of cytokines and chemokines, resulting in the activation of astrocytes and recr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gustin, Audrey, Kirchmeyer, Mélanie, Koncina, Eric, Felten, Paul, Losciuto, Sophie, Heurtaux, Tony, Tardivel, Aubry, Heuschling, Paul, Dostert, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474809/
https://ncbi.nlm.nih.gov/pubmed/26091541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130624
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